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Crosstalk between Gα(i)- and Gα(q)-coupled receptors is mediated by Gβγ exchange

Activation of Gα(i)-coupled receptors often causes enhancement of the inositol phosphate signal triggered by Gα(q)-coupled receptors. To investigate the mechanism of this synergistic receptor crosstalk, we studied the Gα(i)-coupled adenosine A(1) and α(2C) adrenergic receptors and the Gα(q)-coupled...

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Detalhes bibliográficos
Main Authors: Quitterer, Ursula, Lohse, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17933/
https://ncbi.nlm.nih.gov/pubmed/10485876
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