Topographical and functional investigation of Escherichia coli penicillin-binding protein 1b by alanine stretch scanning mutagenesis.

Penicillin-binding proteins (PBPs) are the targets of beta-lactam antibiotics. We have used a systematic five-alanine substitution method (called ASS [alanine stretch scanning] mutagenesis) to investigate the functional or structural role of various stretches of amino acids in the PBP1b of Escherich...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Lefèvre, F, Rémy, M H, Masson, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9244263/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.15.4761-4767.1997
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