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A novel resistance mechanism against beta-lactams in Streptococcus pneumoniae involves CpoA, a putative glycosyltransferase.

Piperacillin resistance in Streptococcus pneumoniae was mediated by mutations in a novel gene, cpoA, that also confer transformation deficiency and a decrease in penicillin-binding protein la. cpoA is part of an operon located downstream of the primary sigma factor of S. pneumoniae. The deduced prot...

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Hlavní autoři: Grebe, T, Paik, J, Hakenbeck, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC179116/
https://ncbi.nlm.nih.gov/pubmed/9150233
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