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The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model
BACKGROUND: Intranasal inoculation of Streptococcus pneumoniae D39 serotype 2 causes fatal pneumonia in mice. The cytotoxic and inflammatory properties of pneumolysin (PLY) have been implicated in the pathogenesis of pneumococcal pneumonia. METHODS: To examine the role of PLY in this experimental mo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1790890/ https://ncbi.nlm.nih.gov/pubmed/17257395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-3 |
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