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Protection against Pneumococcal Pneumonia in Mice by Monoclonal Antibodies to Pneumolysin

Pneumolysin (PLY) is an important virulence factor of Streptococcus pneumoniae. We examined the ability of three murine monoclonal antibodies (MAbs) to PLY (PLY-4, PLY-5, and PLY-7) to affect the course of pneumococcal pneumonia in mice. The intravenous administration of antibodies PLY-4 and PLY-7 p...

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Bibliografiske detaljer
Main Authors: García-Suárez, María del Mar, Cima-Cabal, María Dolores, Flórez, Noelia, García, Pilar, Cernuda-Cernuda, Rafael, Astudillo, Aurora, Vázquez, Fernando, De Los Toyos, Juan R., Méndez, F. Javier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC470670/
https://ncbi.nlm.nih.gov/pubmed/15271913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4534-4540.2004
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