Protection against Pneumococcal Pneumonia in Mice by Monoclonal Antibodies to Pneumolysin

Pneumolysin (PLY) is an important virulence factor of Streptococcus pneumoniae. We examined the ability of three murine monoclonal antibodies (MAbs) to PLY (PLY-4, PLY-5, and PLY-7) to affect the course of pneumococcal pneumonia in mice. The intravenous administration of antibodies PLY-4 and PLY-7 p...

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Detalhes bibliográficos
Main Authors: García-Suárez, María del Mar, Cima-Cabal, María Dolores, Flórez, Noelia, García, Pilar, Cernuda-Cernuda, Rafael, Astudillo, Aurora, Vázquez, Fernando, De Los Toyos, Juan R., Méndez, F. Javier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470670/
https://ncbi.nlm.nih.gov/pubmed/15271913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4534-4540.2004
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