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Protection against Pneumococcal Pneumonia in Mice by Monoclonal Antibodies to Pneumolysin

Pneumolysin (PLY) is an important virulence factor of Streptococcus pneumoniae. We examined the ability of three murine monoclonal antibodies (MAbs) to PLY (PLY-4, PLY-5, and PLY-7) to affect the course of pneumococcal pneumonia in mice. The intravenous administration of antibodies PLY-4 and PLY-7 p...

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Salvato in:
Pubblicato in:Infect Immun
Autori principali: García-Suárez, María del Mar, Cima-Cabal, María Dolores, Flórez, Noelia, García, Pilar, Cernuda-Cernuda, Rafael, Astudillo, Aurora, Vázquez, Fernando, De Los Toyos, Juan R., Méndez, F. Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2004
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15271913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.8.4534-4540.2004
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