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SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy
Cyclin D1 is an allosteric regulator for cyclin-dependent kinases 4 and 6 (CDK4/6). The cyclin D/CDK4 kinase promotes G1/S transition through the posttranslational modification and the subsequent inactivation of the retinoblastoma (Rb) protein and related family members (p107 and p130). Accumulation...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1790704/ https://ncbi.nlm.nih.gov/pubmed/17224055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-2-2 |
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