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Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae.

In an effort to characterize the diversity of mechanisms involved in cellular self-protection against the antitumor antibiotic mitomycin C (MC), DNA fragments from the producing organism (Streptomyces lavendulae) were introduced into Streptomyces lividans and transformants were selected for resistan...

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Détails bibliographiques
Auteurs principaux: Sheldon, P J, Johnson, D A, August, P R, Liu, H W, Sherman, D H
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC178896/
https://ncbi.nlm.nih.gov/pubmed/9045843
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