A Gly145Ser substitution in the transcriptional activator PrfA causes constitutive overexpression of virulence factors in Listeria monocytogenes.

Virulence genes in Listeria monocytogenes are coordinately expressed under the control of the transcriptional activator PrfA, encoded by prfA, a member of the cyclic AMP (cAMP) receptor protein (CRP)/FNR family of bacterial regulators. Strain P14-A is a spontaneous mutant of L. monocytogenes serovar...

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Pubblicato in:	J Bacteriol
Autori principali:	Ripio, M T, Domínguez-Bernal, G, Lara, M, Suárez, M, Vazquez-Boland, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9045810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.5.1533-1540.1997
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