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A Gly145Ser substitution in the transcriptional activator PrfA causes constitutive overexpression of virulence factors in Listeria monocytogenes.

Virulence genes in Listeria monocytogenes are coordinately expressed under the control of the transcriptional activator PrfA, encoded by prfA, a member of the cyclic AMP (cAMP) receptor protein (CRP)/FNR family of bacterial regulators. Strain P14-A is a spontaneous mutant of L. monocytogenes serovar...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Ripio, M T, Domínguez-Bernal, G, Lara, M, Suárez, M, Vazquez-Boland, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9045810/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.5.1533-1540.1997
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