Investigation of ribosome binding by the Shiga toxin A1 subunit, using competition and site-directed mutagenesis.
The enzymatic subunit of Shiga toxin (StxA1) is a member of the ribosome-inactivating protein (RIP) family, which includes the ricin A chain as well as other examples of plant toxins. StxA1 catalytically depurinates a well-conserved GAGA tetra-loop of 28S rRNA which lies in the acceptor site of euka...
Guardat en:
| Publicat a: | J Bacteriol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9023224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.4.1368-1374.1997 |
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