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Asymmetry of intronic pre-miRNA structures in functional RISC assembly
The two oligonucleotide strands of a siRNA duplex are functionally asymmetric in assembling the RNAi effector, RNA-induced gene silencing complex (RISC). Based on this asymmetric RISC assembly model in vitro, formation of a microRNA (miRNA) and complementary miRNA (miRNA*) duplex was proposed to be...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1788082/ https://ncbi.nlm.nih.gov/pubmed/16005165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2005.04.036 |
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