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Pristinamycin I biosynthesis in Streptomyces pristinaespiralis: molecular characterization of the first two structural peptide synthetase genes.

Two genes involved in the biosynthesis of the depsipeptide antibiotics pristinamycins I (PI) produced by Streptomyces pristinaespiralis were cloned and sequenced. The 1.7-kb snbA gene encodes a 3-hydroxypicolinic acid:AMP ligase, and the 7.7-kb snbC gene encodes PI synthetase 2, responsible for inco...

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Detalhes bibliográficos
Main Authors: de Crécy-Lagard, V, Blanc, V, Gil, P, Naudin, L, Lorenzon, S, Famechon, A, Bamas-Jacques, N, Crouzet, J, Thibaut, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC178751/
https://ncbi.nlm.nih.gov/pubmed/9006024
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