Pristinamycin I biosynthesis in Streptomyces pristinaespiralis: molecular characterization of the first two structural peptide synthetase genes.

Two genes involved in the biosynthesis of the depsipeptide antibiotics pristinamycins I (PI) produced by Streptomyces pristinaespiralis were cloned and sequenced. The 1.7-kb snbA gene encodes a 3-hydroxypicolinic acid:AMP ligase, and the 7.7-kb snbC gene encodes PI synthetase 2, responsible for inco...

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Dades bibliogràfiques

Publicat a:	J Bacteriol
Autors principals:	de Crécy-Lagard, V, Blanc, V, Gil, P, Naudin, L, Lorenzon, S, Famechon, A, Bamas-Jacques, N, Crouzet, J, Thibaut, D
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9006024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.3.705-713.1997
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