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The glutamic acid residue at amino acid 261 of the alpha subunit is a determinant of the intrinsic efficiency of RNA polymerase at the metE core promoter in Escherichia coli.

A mutation in the rpoA gene (which encodes the alpha subunit of RNA polymerase) that changed the glutamic acid codon at position 261 to a lysine codon decreased the level of expression of a metE-lacZ fusion 10-fold; this decrease was independent of the MetR-mediated activation of metE-lacZ. Glutamin...

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Bibliografische gegevens
Hoofdauteurs: Jafri, S, Urbanowski, M L, Stauffer, G V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC178580/
https://ncbi.nlm.nih.gov/pubmed/8955301
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