A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes

We performed a multitiered, case-control association study of psoriasis in three independent sample sets of white North American individuals (1,446 cases and 1,432 controls) with 25,215 genecentric single-nucleotide polymorphisms (SNPs) and found a highly significant association with an IL12B 3′-unt...

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Hauptverfasser: Cargill, Michele , Schrodi, Steven J. , Chang, Monica , Garcia, Veronica E. , Brandon, Rhonda , Callis, Kristina P. , Matsunami, Nori , Ardlie, Kristin G. , Civello, Daniel , Catanese, Joseph J. , Leong, Diane U. , Panko, Jackie M. , McAllister, Linda B. , Hansen, Christopher B. , Papenfuss, Jason , Prescott, Stephen M. , White, Thomas J. , Leppert, Mark F. , Krueger, Gerald G. , Begovich, Ann B. 
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785338/
https://ncbi.nlm.nih.gov/pubmed/17236132
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