Identification of the Genetic Basis for Complex Disorders by Use of Pooling-Based Genomewide Single-Nucleotide–Polymorphism Association Studies

We report the development and validation of experimental methods, study designs, and analysis software for pooling-based genomewide association (GWA) studies that use high-throughput single-nucleotide–polymorphism (SNP) genotyping microarrays. We first describe a theoretical framework for establishi...

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Main Authors: Pearson, John V., Huentelman, Matthew J., Halperin, Rebecca F., Tembe, Waibhav D., Melquist, Stacey, Homer, Nils, Brun, Marcel, Szelinger, Szabolcs, Coon, Keith D., Zismann, Victoria L., Webster, Jennifer A., Beach, Thomas, Sando, Sigrid B., Aasly, Jan O., Heun, Reinhard, Jessen, Frank, Kölsch, Heike, Tsolaki, Magdalini, Daniilidou, Makrina, Reiman, Eric M., Papassotiropoulos, Andreas, Hutton, Michael L., Stephan, Dietrich A., Craig, David W.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785308/
https://ncbi.nlm.nih.gov/pubmed/17160900
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