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Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling

Notch/RBP-J signaling is required for generation of early T progenitors (ETP) and promotion of double-negative (DN) 4 cells from DN3 cells in thymocyte differentiation. However, whether Notch affects other steps during thymocyte differentiation remains unknown. Msx2-interacting nuclear target protei...

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Main Authors: Tsuji, Masayuki, Shinkura, Reiko, Kuroda, Kazuki, Yabe, Daisuke, Honjo, Tasuku
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785279/
https://ncbi.nlm.nih.gov/pubmed/17242367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610520104
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