Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene

The tyrosine phosphatase PTPN22 allele 1858T has been associated with rheumatoid arthritis (RA) and other autoimmune diseases. RA is the most frequent of those multifactorial diseases. The RA association was usually restricted to serum rheumatoid factor positive disease (RF(+)). No interaction was s...

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Autors principals: Michou, Laëtitia, Lasbleiz, Sandra, Rat, Anne-Christine, Migliorini, Paola, Balsa, Alejandro, Westhovens, René, Barrera, Pilar, Alves, Helena, Pierlot, Céline, Glikmans, Elodie, Garnier, Sophie, Dausset, Jean, Vaz, Carlos, Fernandes, Manuela, Petit-Teixeira, Elisabeth, Lemaire, Isabelle, Pascual-Salcedo, Dora, Bombardieri, Stefano, Dequeker, Jan, Radstake, Timothy R., Van Riel, Piet, van de Putte, Leo, Lopes-Vaz, Antonio, Prum, Bernard, Bardin, Thomas, Dieudé, Philippe, Cornélis, François
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785249/
https://ncbi.nlm.nih.gov/pubmed/17237219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610250104
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