The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study

The integrin αvβ3, whose αv subunit is encoded by the ITGAV gene, plays a key role in angiogenesis. Hyperangiogenesis is involved in rheumatoid arthritis (RA) and the ITGAV gene is located in 2q31, one of the suggested RA susceptibility loci. Our aim was to test the ITGAV gene for association and li...

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Autori principali: Jacq, Laurent, Garnier, Sophie, Dieudé, Philippe, Michou, Laëtitia, Pierlot, Céline, Migliorini, Paola, Balsa, Alejandro, Westhovens, René, Barrera, Pilar, Alves, Helena, Vaz, Carlos, Fernandes, Manuela, Pascual-Salcedo, Dora, Bombardieri, Stefano, Dequeker, Jan, Radstake, Timothy R, Van Riel, Piet, van de Putte, Leo, Lopes-Vaz, Antonio, Glikmans, Elodie, Barbet, Sandra, Lasbleiz, Sandra, Lemaire, Isabelle, Quillet, Patrick, Hilliquin, Pascal, Teixeira, Vitor Hugo, Petit-Teixeira, Elisabeth, Mbarek, Hamdi, Prum, Bernard, Bardin, Thomas, Cornélis, François
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206364/
https://ncbi.nlm.nih.gov/pubmed/17615072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2221
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