The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study

The integrin αvβ3, whose αv subunit is encoded by the ITGAV gene, plays a key role in angiogenesis. Hyperangiogenesis is involved in rheumatoid arthritis (RA) and the ITGAV gene is located in 2q31, one of the suggested RA susceptibility loci. Our aim was to test the ITGAV gene for association and li...

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Hlavní autoři: Jacq, Laurent, Garnier, Sophie, Dieudé, Philippe, Michou, Laëtitia, Pierlot, Céline, Migliorini, Paola, Balsa, Alejandro, Westhovens, René, Barrera, Pilar, Alves, Helena, Vaz, Carlos, Fernandes, Manuela, Pascual-Salcedo, Dora, Bombardieri, Stefano, Dequeker, Jan, Radstake, Timothy R, Van Riel, Piet, van de Putte, Leo, Lopes-Vaz, Antonio, Glikmans, Elodie, Barbet, Sandra, Lasbleiz, Sandra, Lemaire, Isabelle, Quillet, Patrick, Hilliquin, Pascal, Teixeira, Vitor Hugo, Petit-Teixeira, Elisabeth, Mbarek, Hamdi, Prum, Bernard, Bardin, Thomas, Cornélis, François
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206364/
https://ncbi.nlm.nih.gov/pubmed/17615072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2221
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