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Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1
Wwtr1 is a widely expressed 14-3-3-binding protein that regulates the activity of several transcription factors involved in development and disease. To elucidate the physiological role of Wwtr1, we generated Wwtr1(−/−) mice by homologous recombination. Surprisingly, although Wwtr1 is known to regula...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785239/ https://ncbi.nlm.nih.gov/pubmed/17251353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605266104 |
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