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Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

Wwtr1 is a widely expressed 14-3-3-binding protein that regulates the activity of several transcription factors involved in development and disease. To elucidate the physiological role of Wwtr1, we generated Wwtr1(−/−) mice by homologous recombination. Surprisingly, although Wwtr1 is known to regula...

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Detalhes bibliográficos
Main Authors: Hossain, Zakir, Ali, Safiah Mohamed, Ko, Hui Ling, Xu, Jianliang, Ng, Chee Peng, Guo, Ke, Qi, Zeng, Ponniah, Sathivel, Hong, Wanjin, Hunziker, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785239/
https://ncbi.nlm.nih.gov/pubmed/17251353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605266104
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