Transcriptional regulation of Salmonella virulence: a PhoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP.

A mutation in the phoP/phoQ locus (pho-24) that results in unregulated expression of PhoP-activated genes (phenotype PhoP constitutive [PhoP(c)]) was mapped to phoQ. Change of a Thr to Ile at position 48 of PhoQ was responsible for the PhoP(c) phenotype (attenuation of mouse virulence, defects in ep...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Gunn, J S, Hohmann, E L, Miller, S I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.21.6369-6373.1996
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