Transcriptional regulation of Salmonella virulence: a PhoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP.

A mutation in the phoP/phoQ locus (pho-24) that results in unregulated expression of PhoP-activated genes (phenotype PhoP constitutive [PhoP(c)]) was mapped to phoQ. Change of a Thr to Ile at position 48 of PhoQ was responsible for the PhoP(c) phenotype (attenuation of mouse virulence, defects in ep...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Gunn, J S, Hohmann, E L, Miller, S I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.21.6369-6373.1996
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!