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Insights Learned from L457((3.43))R, an Activating Mutant of the Human Lutropin Receptor
The L457((3.43))R mutation of the hLHR was initially identified in a Brazilian boy with gonadotropin-independent precocious puberty. As would be expected, L457((3.43))R, when expressed in 293 cells, caused a marked elevation in basal cAMP levels. Interestingly, in spite of the fact that the elevated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785107/ https://ncbi.nlm.nih.gov/pubmed/17055147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2005.11.053 |
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