WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus–truncated CXCR4

WHIM(warts, hypogammaglobulinemia, recurrent bacterial infection, and myelokathexis) syndrome is a rare immunodeficiency caused in many cases by autosomal dominant C-terminal truncation mutations in the chemokine receptor CXCR4. A prominent and unexplained feature of WHIM is myelokathexis (hypercell...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kawai, Toshinao, Choi, Uimook, Cardwell, Lanise, DeRavin, Suk See, Naumann, Nora, Whiting-Theobald, Narda L., Linton, Gilda F., Moon, Jaehyun, Murphy, Philip M., Malech, Harry L.
Format:	Artigo
Language:	Inglês
Published:	American Society of Hematology 2007
Subjects:	Hematopoiesis
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1785067/ https://ncbi.nlm.nih.gov/pubmed/16946301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-025296
Tags:	Add Tag No Tags, Be the first to tag this record!

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus–truncated CXCR4

Similar Items