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Directed insertion of a selectable marker into a circular plasmid of Borrelia burgdorferi.

Studies of the biology of Borrelia burgdorferi and the pathogenesis of Lyme disease are severely limited by the current lack of genetic tools. As an initial step toward facile genetic manipulation of this pathogenic spirochete, we have investigated gene inactivation by allelic exchange using a mutat...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Rosa, P, Samuels, D S, Hogan, D, Stevenson, B, Casjens, S, Tilly, K
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8830691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.20.5946-5953.1996
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