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Directed insertion of a selectable marker into a circular plasmid of Borrelia burgdorferi.

Studies of the biology of Borrelia burgdorferi and the pathogenesis of Lyme disease are severely limited by the current lack of genetic tools. As an initial step toward facile genetic manipulation of this pathogenic spirochete, we have investigated gene inactivation by allelic exchange using a mutat...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Rosa, P, Samuels, D S, Hogan, D, Stevenson, B, Casjens, S, Tilly, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8830691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.20.5946-5953.1996
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