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Distance Measurements by Fluorescence Energy Homotransfer: Evaluation in T4 Lysozyme and Correlation with Dipolar Coupling between Spin Labels

We demonstrate the feasibility and practical limitations of using steady-state anisotropy to determine distances from fluorescence homotransfer in the context of a protein of known crystal structure. Eight double mutants of T4 lysozyme spanning the distance range between 20 Å and 50 Å were labeled w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zou, Ping, Surendhran, Kavitha, Mchaourab, Hassane S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783887/
https://ncbi.nlm.nih.gov/pubmed/17142264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.098913
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