Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

BACKGROUND: Recent attention has focused on understanding the role of the brain-renin-angiotensin-system (RAS) in stroke and neurodegenerative diseases. Direct evidence of a role for the brain-RAS in Parkinson's disease (PD) comes from studies demonstrating the neuroprotective effect of RAS inh...

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Bibliografiske detaljer
Main Authors: Grammatopoulos, Tom N, Jones, Susan M, Ahmadi, Ferogh A, Hoover, Brian R, Snell, Lawrence D, Skoch, Jesse, Jhaveri, Vimal V, Poczobutt, Andy M, Weyhenmeyer, James A, Zawada, W Michael
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783655/
https://ncbi.nlm.nih.gov/pubmed/17224059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-2-1
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