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The non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia coli is required for folding and/or stability of the penicillin-binding module and the membrane-anchoring module confers cell septation activity on the folded structure.

The ftsI-encoded multimodular class B penicillin-binding protein 3 (PBP3) is a key element of the cell septation machinery of Escherichia coli. Altered ftsI genes were overexpressed, and the gene products were analyzed with respect to the level of production, stability, penicillin affinity, and cell...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Goffin, C, Fraipont, C, Ayala, J, Terrak, M, Nguyen-Distèche, M, Ghuysen, J M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8808928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.18.5402-5409.1996
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