Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium.

Among its penicillin-binding proteins (PBPs), Enterococcus faecium possesses a low-affinity PBP5, PBP5fm, which is the main target involved in beta-lactam resistance. A 7.7-kb EcoRI chromosomal fragment of E. faecium D63r containing the pbp5fm gene was cloned and sequenced. Two open reading frames (...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Zorzi, W, Zhou, X Y, Dardenne, O, Lamotte, J, Raze, D, Pierre, J, Gutmann, L, Coyette, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178279/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8759860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.16.4948-4957.1996
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