Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium.

Among its penicillin-binding proteins (PBPs), Enterococcus faecium possesses a low-affinity PBP5, PBP5fm, which is the main target involved in beta-lactam resistance. A 7.7-kb EcoRI chromosomal fragment of E. faecium D63r containing the pbp5fm gene was cloned and sequenced. Two open reading frames (...

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Библиографические подробности
Главные авторы: Zorzi, W, Zhou, X Y, Dardenne, O, Lamotte, J, Raze, D, Pierre, J, Gutmann, L, Coyette, J
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC178279/
https://ncbi.nlm.nih.gov/pubmed/8759860
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