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Costimulation and Pancreatic Autoimmunity: The PD-1/PD-L Conundrum

T cell activation is a complex process that requires a multitude of interactions between antigen-presenting cells (APC) and T cells. The primary signal is provided via the binding of the antigen (Ag) presented by the major histocompatibility complex (MHC) on an APC and the T cell receptor (TCR). Thi...

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Autors principals: Yadav, Deepak, Sarvetnick, Nora
Format: Artigo
Idioma:Inglês
Publicat: SBDR - Society for Biomedical Diabetes Research 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783571/
https://ncbi.nlm.nih.gov/pubmed/17491706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2006.3.6
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