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Effect of Losartan on the mRNA Expressions of MT3-MMP and TIMP-2 in Diabetic Kidneys

BACKGROUND and OBJECTIVES: The renin-angiotensin system plays a critical role in circulatory homoeostasis. Evidence has emerged that suggests a pathologic role for angiotensin II in patients with kidney disease. Losartan is an antagonist of angiotensin II and blocks the angiotensin II type-1 recepto...

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Detalhes bibliográficos
Main Authors: Ding, He-Lin, Xu, Ming-Tong, Guo, Ying, Chen, Long, Zhang, Shao-Ling, Li, Feng, Fu, Zu-Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783568/
https://ncbi.nlm.nih.gov/pubmed/17491697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2005.2.216
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