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Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake

A binary complex of the ammonia channel Amt1 from Methanococcus jannaschii and its cognate P(II) signalling protein GlnK1 has been produced and characterized. Complex formation is prevented specifically by the effector molecules Mg-ATP and 2-ketoglutarate. Single-particle electron microscopy of the...

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Main Authors: Yildiz, Özkan, Kalthoff, Christoph, Raunser, Stefan, Kühlbrandt, Werner
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783471/
https://ncbi.nlm.nih.gov/pubmed/17203075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601492
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