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Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake

A binary complex of the ammonia channel Amt1 from Methanococcus jannaschii and its cognate P(II) signalling protein GlnK1 has been produced and characterized. Complex formation is prevented specifically by the effector molecules Mg-ATP and 2-ketoglutarate. Single-particle electron microscopy of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yildiz, Özkan, Kalthoff, Christoph, Raunser, Stefan, Kühlbrandt, Werner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783471/
https://ncbi.nlm.nih.gov/pubmed/17203075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601492
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