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Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake

A binary complex of the ammonia channel Amt1 from Methanococcus jannaschii and its cognate P(II) signalling protein GlnK1 has been produced and characterized. Complex formation is prevented specifically by the effector molecules Mg-ATP and 2-ketoglutarate. Single-particle electron microscopy of the...

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Detalhes bibliográficos
Main Authors: Yildiz, Özkan, Kalthoff, Christoph, Raunser, Stefan, Kühlbrandt, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783471/
https://ncbi.nlm.nih.gov/pubmed/17203075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601492
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