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Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad

Removal and repair of DNA damage by the nucleotide excision repair pathway requires two sequential incision reactions, which are achieved by the endonuclease UvrC in eubacteria. Here, we describe the crystal structure of the C-terminal half of UvrC, which contains the catalytic domain responsible fo...

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Detalhes bibliográficos
Main Authors: Karakas, Erkan, Truglio, James J, Croteau, Deborah, Rhau, Benjamin, Wang, Liqun, Van Houten, Bennett, Kisker, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783470/
https://ncbi.nlm.nih.gov/pubmed/17245438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601497
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