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Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad

Removal and repair of DNA damage by the nucleotide excision repair pathway requires two sequential incision reactions, which are achieved by the endonuclease UvrC in eubacteria. Here, we describe the crystal structure of the C-terminal half of UvrC, which contains the catalytic domain responsible fo...

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Autori principali: Karakas, Erkan, Truglio, James J, Croteau, Deborah, Rhau, Benjamin, Wang, Liqun, Van Houten, Bennett, Kisker, Caroline
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783470/
https://ncbi.nlm.nih.gov/pubmed/17245438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601497
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