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Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex

In Drosophila and mammals, insulin signalling can increase growth, progression through G1/S, cell size and tissue size. Here, we analyse the way insulin affects cell size and cell-cycle progression in two haemocyte-derived Drosophila cell lines. Surprisingly, we find that although insulin increases...

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Detalhes bibliográficos
Main Authors: Wu, Mary Y W, Cully, Megan, Andersen, Ditte, Leevers, Sally J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783464/
https://ncbi.nlm.nih.gov/pubmed/17183368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601487
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