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The ubiquitin–proteasome system regulates membrane fusion of yeast vacuoles

Ubiquitination is known to regulate early stages of intracellular vesicular transport, without proteasomal involvement. We now show that, in yeast, ubiquitination regulates a late-stage, membrane fusion, with proteasomal involvement. A known proteasome mutant had a vacuolar fragmentation phenotype i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kleijnen, Maurits F, Kirkpatrick, Donald S, Gygi, Steven P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783458/
https://ncbi.nlm.nih.gov/pubmed/17183369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601486
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