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The ubiquitin–proteasome system regulates membrane fusion of yeast vacuoles

Ubiquitination is known to regulate early stages of intracellular vesicular transport, without proteasomal involvement. We now show that, in yeast, ubiquitination regulates a late-stage, membrane fusion, with proteasomal involvement. A known proteasome mutant had a vacuolar fragmentation phenotype i...

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Detalhes bibliográficos
Main Authors: Kleijnen, Maurits F, Kirkpatrick, Donald S, Gygi, Steven P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783458/
https://ncbi.nlm.nih.gov/pubmed/17183369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601486
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