Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4(+) T-regulatory cells and systemic collapse of antitumour immunity

We investigated the relationship between transforming growth factor-β (TGF-β)-secreting T-regulatory (Tr) cells and anti-B16 melanoma immunity, and studied the association of early cytokines expressed at tumour sites with the generation of Tr cells. A large number of CD4(+) Tr cells producing interl...

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Hlavní autoři: Seo, Naohiro, Hayakawa, Satoshi, Takigawa, Masahiro, Tokura, Yoshiki
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2001
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783257/
https://ncbi.nlm.nih.gov/pubmed/11529935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01279.x
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