Streptococcal inhibitor of complement (SIC) inhibits the membrane attack complex by preventing uptake of C567 onto cell membranes

Streptococcal inhibitor of complement (SIC) was first described in 1996 as a putative inhibitor of the membrane attack complex of complement (MAC). SIC is a 31 000 MW protein secreted in large quantities by the virulent Streptococcus pyogenes strains M1 and M57, and is encoded by a gene which is ext...

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Autori principali: Fernie-King, Barbara A, Seilly, David J, Willers, Christine, Würzner, Reinhard, Davies, Alexandra, Lachmann, Peter J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783247/
https://ncbi.nlm.nih.gov/pubmed/11454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01249.x
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