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The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo

Macrophages (Mφ) play a key role in innate and acquired immunity. The study of Mφ biology has been hampered by the absence of suitable gene regulatory sequences for the overexpression of heterologous genes in Mφ. The human CD68 gene encodes a glycoprotein that is expressed in monocytes and Mφ, and t...

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Detalhes bibliográficos
Main Authors: Gough, Peter J, Gordon, Siamon, Greaves, David R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783239/
https://ncbi.nlm.nih.gov/pubmed/11454064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01256.x
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