Refocusing of B-cell responses following a single amino acid substitution in an antigen

Intranasal immunization of BALB/c strain mice was carried out using baculovirus-derived human chorionic gonadotrophin (hCG) β-chain, together with Escherichia coli heat-labile enterotoxin. Gonadotrophin-reactive immunoglobulin A (IgA) was induced in a remote mucosal site, the lung, in addition to a...

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Detalhes bibliográficos
Main Authors: Chiesa, Marta Dalla, Martensen, Pia M, Simmons, Cameron, Porakishvili, Nino, Justesen, Just, Dougan, Gordon, Roitt, Ivan M, Delves, Peter J, Lund, Torben
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783232/
https://ncbi.nlm.nih.gov/pubmed/11412304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01242.x
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