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Clonal anergy induced in a CD8(+) hapten-specific cytotoxic T-cell clone by an altered hapten-peptide ligand
Clonal T-cell anergy has been proposed as a mechanism to ensure peripheral tolerance in vivo. Anergy has been reported to result from T cell activation with inappropriate antigen-presenting cells (APC) or, in the case of CD4(+) T cells, also by altered peptide ligands. This study reveals that altere...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Blackwell Science Inc
2001
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783159/ https://ncbi.nlm.nih.gov/pubmed/11168631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01146.x |
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