Antigen dose, type of antigen-presenting cell and time of differentiation contribute to the T helper 1/T helper 2 polarization of naive T cells

Antigenic encounter by T cells induces immunological synapse formation and T-cell activation. Using different concentrations of toxic shock syndrome toxin-1 (TSST-1) as stimulus, we examined the capacities of dendritic cells (DC) and macrophages (Mφ) to prime syngeneic naive T cells. DCs were, under...

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Bibliografiske detaljer
Main Authors: Rothoeft, T, Gonschorek, A, Bartz, H, Anhenn, O, Schauer, U
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783073/
https://ncbi.nlm.nih.gov/pubmed/14632640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2003.01758.x
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