The role of antigen-presenting cells and interleukin-12 in the priming of antigen-specific CD4(+) T cells by immune stimulating complexes

Immune stimulating complexes (ISCOMs) containing the saponin adjuvant Quil A are vaccine adjuvants that promote a wide range of immune responses in vivo, including delayed-type hypersensitivity (DTH) and the secretion of both T helper 1 (Th1) and Th2 cytokines. However, the antigen-presenting cell (...

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Main Authors: Robson, Neil C, Beacock-Sharp, Helen, Donachie, Anne M, Mowat, Allan MCI
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2003
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783021/
https://ncbi.nlm.nih.gov/pubmed/12941146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01705.x
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