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Arginase and autoimmune inflammation in the central nervous system

Using a high throughput gene microarray technology that detects ∼22 000 genes, we found that arginase I was the most significantly up-regulated gene in the murine spinal cord during experimental autoimmune encephalomyelitis (EAE). By Northern blot and arginase enzyme assay, we detected high levels o...

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Bibliographic Details
Main Authors: Xu, Lingyun, Hilliard, Brendan, Carmody, Ruaidhrí J, Tsabary, Galit, Shin, Hyunshun, Christianson, David W, Chen, Youhai H
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783013/
https://ncbi.nlm.nih.gov/pubmed/12941151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01713.x
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