TRAF6-NF-κB pathway is essential for interleukin-1-induced TLR2 expression and its functional response to TLR2 ligand in murine hepatocytes

We have previously reported that the expressions of TLR2 and TLR4 mRNA are differentially regulated in mouse liver and in the parenchymal cells. In the present study, we investigated the mechanism of the up-regulatory effects of interleukin-1α (IL-1α), tumour necrosis factor-α (TNF-α), lipopolysacch...

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Detalhes bibliográficos
Main Authors: Matsumura, Takayuki, Degawa, Takahiro, Takii, Takemasa, Hayashi, Hidetoshi, Okamoto, Takashi, Inoue, Jun-ichiro, Onozaki, Kikuo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782941/
https://ncbi.nlm.nih.gov/pubmed/12709026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01627.x
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